An interdisciplinary research lab
The CRM2 (Cristallographie, Résonance Magnétique et Modélisations) laboratory is an interdisciplinary UMR between CNRS and Université de Lorraine (UL). For CNRS, it is linked to the Institut de Physique (section 5) and to the Institut de Chimie (section 13). For UL it belongs to the scientific Pole “Chimie et Physique Moléculaire” (CPM).
Research
The main scientific aim is to to develop original and complementary methods and instruments for the study of the structure and dynamics of molecular and biomolecular materials in order to understand structure-property and structure-function relationships.
Crystallography, X-ray and NMR/NQR methods and instrumentation, electron density modeling, diffraction under constraints (light, pressure, electric field) are developed together with applications in:
- Material science (e.g. photosensitive functional materials, low dimensional materials, multiferroic materials, porous materials, molecular materials…)
- Physics (phase transitions, molecular magnetism, piezoelectricity, …)
- Chemistry (Chemical bonding, metal-ligand, macromolecule-ligands, weak intermolecular interactions, crystal engineering, …)
- Life sciences (enzymes, detoxification, xenobiotics, secondary metabolites, reaction intermediates, protein-ligand, protein-protein and protein-DNA interactions, molecular recognition, molecular modelling, …)
- Health sciences (crystallization, co-crystallization and modeling of physicochemical properties of pharmaceutical solids of APIs (Active Pharmaceutical Ingredients))
Teaching
CRM2 is highly involved in teaching at all levels. We organise regularly national (CNRS) and international schools on crystallography and offer training to research engineers and doctoral students of other laboratories.
At the University of Lorraine the members of CRM2 teach at the Faculty of Sciences and Technologies in the bachelor and master courses in physics, chemistry, life sciences, and earth sciences.
Our two platforms
The CRM2 is in charge of two platforms of X-ray diffraction (XRD) and nuclear magnetic resonance (NMR).
Our 3 teams
BioMIMIC
Structural Biology, Molecular Interaction Modeling, Crystal Engineering
CRISP
Crystallography and Relationships
Structure-Properties
RMN
NMR methodology