Maître de Conférences

telephone+33 (0)3 72 74 52 58

fax+33 (0)3 83 68 43 47

carriere_icn Career:

(Français) since 12/2011: Associate Professor , lecturer at département Génie Biologie Santé (GBS) from the IUT Nancy Brabois
Researcher at the CRM2 laboratory (Pr. D. Schaniel) in the NMR methodology development team

2009 – 2011: Postdoctoral Researcher, Institute of structural biology, Grenoble, Pr B. Brutscher, “ NMR characterization of structure and dynamics of the bacterial cell wall”

2005 – 2008: Postdoctoral Researcher, Magnetic Resonance Laboratory of Southampton University, Southampton, Pr. M. H. Levitt. “NMR characterization of the first photointermediates of the GPCR Rhodopsin” & “SSNMR methodology developments for selective dipolar recoupling in solids”

2001 – 2004: Doctoral Researcher, TECTOSPIN, Université de Versailles, Pr. F. Taulelle, “Double quantum NMR study of elastomer compatibility” (for MICHELIN company)

recherche_icn Research field:

(Français) – Solution and solid state Nuclear Magnetic Resonance (NMR)
– in-situ photo-NMR
– Nuclear Quadrupole Resonance (NQR)
– DFT calculation of NMR, NQR and IR parameters

Description of research:

My research mainly focusses on the development of nuclear resonance spectroscopy (solid and solution state NMR, NQR) in order to establish and understand the relationship between the molecular structure and the material properties. The originality of our approach lies in the combination of solution and solid state NMR techniques with the information obtained from total X-ray diffraction coupled to Pair Distribution Function analysis (PDF).
I order to interpret in more details the NMR measurements, in terms of structure and dynamics, I apply Density Functional Theory (DFT)to establish structural models and simulate NMR and IR spectra.
I recently started a new research topic, focusing on photo-NMR characterization of photo-commutating materials. In this respect we develop in-situ and ex-situ approaches to perform NMR on photoinduced states in solution and solid state.

Research topics

Detail of the 3 main research topics:
Characterization of structure and dynamics in heterogeneous materials.pdf
« Photo-NMR » characterization of photoactive systems
Methodology and instrumentation in Nuclear Quadrupole Resonance (NQR).pdf

publication_icn Publications:

Gansmuller A., Mikhailov A. A., Kostin G. A., Raya J., Palin C., Woike T. and Schaniel D.
Solid-State Photo-NMR Study on Light-Induced Nitrosyl Linkage Isomers Uncovers Their Structural, Electronic, and Diamagnetic Nature
Analytical Chemistry 94(10) (2022) 4474-4483 DOI link

Rjiba A., Khoder H., Jelassi J., Bouguet-Bonnet S., Gardiennet C., Bendeif E.-E., Gansmuller A., Dorbez-Sridi R.
Differential scanning calorimetry and NMR study of water confined in a mesoporous bioactive glass
Microporous and Mesoporous Materials 316 (2021) 110992 DOI link

Angelini G., Gansmuller A., Pécourneau J., Gasbarri C.
An insight into cyclocurcumin cis-trans isomerization: Kinetics in solution and in the presence of silver nanoparticles
Journal of Molecular Liquids 333 (2021) 116000 DOI link

Mikhailov A. A. , Woike T., Gansmuller A., Schaniel D., Kostin G. A.
Photoinduced linkage isomers in a model ruthenium nitrosyl complex: Identification and assignment of vibrational modes
Spectrochimica Acta, Part A: Molecular Spectroscopy 263 (2021) 120217 DOI link

Berro Y., Gueddida S., Bouizi Y., Bellouard C., Bendeif E.-E., Gansmuller A., Celzard A., Fierro V., Ihiawakrim D., Ersen O., Kassir M., El Haj Hassan F., Lebegue S., Badawi M., Canilho N., Pasc A.
Imprinting isolated single iron atoms onto mesoporous silica by templating with metallosurfactants
Journal of Colloid and Interface Science 573 (2020) 193-203 DOI link

Ajili W., Laurent G. P., Menguy N., Gansmuller A., Huchette S., Auzoux-Bordenave S., Nassif N., and Azais T.
Chemical Heterogeneities within the Disordered Mineral domains of Aragonite Platelets in Nacre from the European Abalone Haliotis tuberculata
Journal of Physical Chemistry C 124(26) (2020) 14118-14130 DOI link

Haffner F., Canilho N., Medronho B., Gardiennet C., Gansmuller A., Pasc A.
In situ follow-up of hybrid alginate-silicate microbeads formation by linear rheology
Physical Chemistry Chemical Physics (2018) DOI link

Deligey F., Bouguet-Bonnet S., Doudouh A., Marande P.-L., Schaniel D., Gansmüller A.
Bridging Structural and Dynamical Models of a Confined Sodium Nitroprusside Complex
The Journal of Physical Chemistry C (2018) DOI link

Wathier L., Venet T., Thomas A., Nunge H., Bonfanti E., Cosnier F., Parietti-Winkler C., Campo P., Tsan P., Bouguet-Bonnet S., Gansmüller A.
Membrane fluidity does not explain how solvents act on the middle-ear reflex
NeuroToxicology 57 (2016) 13-21 DOI link

Bendeif E.-E., Gansmuller A., Hsieh K.-Y., Pillet S., Woike T., Zobel M., Neder R., Bouazaoui M., El Hamzaoui H., Schaniel D.
Structure determination of molecular nanocomposites by combining pair distribution function analysis and solid-state NMR
RSC Advances 5 (2015) 8895-8902 DOI link

Hsieh K.-Y., Bendeif E.-E., Gansmuller A., Pillet S., Woike T., Schaniel D.
Structure and dynamics of guest molecules confined in a mesoporous silica matrix: Complementary NMR and PDFcharacterisation
RSC Advances 3 (2013) 26132-26141 DOI link

Gansmuller A., Simorre J.-P., Hediger S.
Windowed R-PDLF recoupling: A flexible and reliable tool to characterize molecular dynamics
Journal of Magnetic Resonance 234 (2013) 154-164 DOI link

McLean N., Gansmuller A., Concistre M., Brown L., Levitt M., Brown R.
Syntheses of 13C2-labelled 11Z-retinals
Tetrahedron 67 (2011) 8404-8410 DOI link

Gansmuller, A., Concistrè, M., McLean, N., Johannessen, O., Marín-Montesinos, I., Bovee-Geurts, P., Verdegem, P., Lugtenburg, J., Brown, R., DeGrip, W., Levitt, M.
Towards an interpretation of 13C chemical shifts in bathorhodopsin, a functional intermediate of a G-protein coupled receptor
1788 (2009) 1350-1357 DOI link

Concistrè, M., Gansmuller, A., McLean, N., Johannessen, O., Mari?n Montesinos, I., Bovee-Geurts, P., Brown, R., DeGrip, W., Levitt, M.
Light Penetration and Photoisomerization in Rhodopsin studied by Numerical Simulations and Double-Quantum Solid-State NMR Spectroscopy
Journal of the American Chemical Society 131 (2009) 6133-6140 DOI link

Pileio, G., Mamone, S., Mollica, G., Montesinos, I., Gansmuller, A., Carravetta, M., Brown, S., Levitt, M.
Estimation of internuclear couplings in the solid-state NMR of multiple-spin systems. Selective spin echoes and off-magic-angle sample spinning
Chemical Physics Letters 456 (2008) 116-121 DOI link

Concistrè, M., Gansmuller, A., McLean, N., Johannessen, O., Mari?n Montesinos, I., Bovee-Geurts, P., Verdegem, P., Lugtenburg, J., Brown, R., DeGrip, W., Levitt, M.
Double-Quantum 13 C Nuclear Magnetic Resonance of Bathorhodopsin, the First Photointermediate in Mammalian Vision
Journal of the American Chemical Society 130 (2008) 10490-10491 DOI link

Giuseppe Pileio, Maria Concistrè, Neville McLean, Axel Gansmüller, Richard C. D. Brown, and Malcolm H. Levitt
Analytical theory of γ-encoded double-quantum recoupling sequences in solid-state nuclear magnetic resonance
Journal of Magnetic Resonance 186(1) (2007) 65-74 DOI link

Marin-Montesinos, I., Mollica, G., Carravetta, M., Gansmuller, A., Pileio, G., Bechmann, M., Sebald, A., Levitt, M.
Truncated dipolar recoupling in solid-state nuclear magnetic resonance
Chemical Physics Letters 432 (2006) 572-578 DOI link

Lai, W., McLean, N., Gansmuller, A., Verhoeven, M., Antonioli, G., Carravetta, M., Duma, L., Bovee-Geurts, P., Johannessen, O., de Groot, H., Lugtenburg, J., Emsley, L., Brown, S., Brown, R., DeGrip,
Accurate Measurements of 13 C? 13 C J -Couplings in the Rhodopsin Chromophore by Double-Quantum Solid-State NMR Spectroscopy
Journal of the American Chemical Society 128 (2006) 3878-3879 DOI link

Beitone, L., Marrot, J., Loiseau, T., Férey, G., Henry, M., Huguenard, C., Gansmuller, A., Taulelle, F.
MIL-50, an Open-Framework GaPO with a Periodic Pattern of Small Water Ponds and Dry Rubidium Atoms:  a Combined XRD, NMR, and Computational Study
Journal of the American Chemical Society 125 (2003) 1912-1922 DOI link

Beitone, L., Huguenard, C., Gansmuller, A., Henry, M., Taulelle, F., Loiseau, T., Férey, G.
Order-Disorder in the Super-Sodalite Zn 3 Al 6 (PO 4 ) 12 , 4 t ren , 17H 2 O (MIL-74):  A Combined XRD?NMR Assessment
Journal of the American Chemical Society 125 (2003) 9102-9110 DOI link